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Structural basis for recognition of SMRT/N-CoR by the MYND domain and its contribution to AML1/ETO's activity
AML1/ETO results from the t(8;21) associated with 12-15% of acute myeloid leukemia. The AML1/ETO MYND domain mediates interactions with the co-repressors SMRT and N-CoR and contributes to AML1/ETO's ability to repress proliferation and differentiation of primary bone marrow cells as well as to...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2007
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1978186/ https://ncbi.nlm.nih.gov/pubmed/17560331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2007.04.010 |
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