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The death domain kinase RIP has an essential role in DNA damage-induced NF-κB activation

The transcription factor NF-κB is activated when cells are exposed to genotoxic stress. It has been suggested that DNA damage will trigger a cytoplasmic signaling that leads to the activation of IKK and NF-κB, but the signaling components upstream of IKK have not yet been identified. Here we report...

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Bibliografiske detaljer
Main Authors: Hur, Gang Min, Lewis, Joseph, Yang, Qingfeng, Lin, Yong, Nakano, Hiroyasu, Nedospasov, Sergei, Liu, Zheng-gang
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC196033/
https://ncbi.nlm.nih.gov/pubmed/12654725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1062403
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