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The death domain kinase RIP has an essential role in DNA damage-induced NF-κB activation
The transcription factor NF-κB is activated when cells are exposed to genotoxic stress. It has been suggested that DNA damage will trigger a cytoplasmic signaling that leads to the activation of IKK and NF-κB, but the signaling components upstream of IKK have not yet been identified. Here we report...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC196033/ https://ncbi.nlm.nih.gov/pubmed/12654725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1062403 |
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