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Evidence that binding of C5 protein to P RNA enhances ribozyme catalysis by influencing active site metal ion affinity
The RNA subunit (P RNA) of the bacterial RNase P ribonucleoprotein is a ribozyme that catalyzes the Mg-dependent hydrolysis of pre-tRNA, but it requires an essential protein cofactor (P protein) in vivo that enhances substrate binding affinities and catalytic rates in a substrate dependent manner. P...
Gorde:
| Egile Nagusiak: | , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Cold Spring Harbor Laboratory Press
2007
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950769/ https://ncbi.nlm.nih.gov/pubmed/17652407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.571007 |
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