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Evidence for a polynuclear metal ion binding site in the catalytic domain of ribonuclease P RNA

Interactions with divalent metal ions are essential for the folding and function of the catalytic RNA component of the tRNA processing enzyme ribonuclease P (RNase P RNA). However, the number and location of specific metal ion interactions in this large, highly structured RNA are poorly understood....

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Autori principali: Christian, Eric L., Kaye, Nicholas M., Harris, Michael E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC125996/
https://ncbi.nlm.nih.gov/pubmed/11980722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.9.2253
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