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Evidence for a Non-Catalytic Ion-Binding Site in Multiple RNA-Dependent RNA Polymerases

A high-affinity divalent cation-binding site located proximal to the catalytic center has been identified in several RNA-dependent RNA polymerases (RdRps), but the characteristics of such a site have not been systematically studied. Here, all available polymerase structures that follow the hand-like...

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Detalhes bibliográficos
Main Authors: Mönttinen, Heli A. M., Ravantti, Janne J., Poranen, Minna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3394715/
https://ncbi.nlm.nih.gov/pubmed/22792374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040581
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