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Mapping metal-binding sites in the catalytic domain of bacterial RNase P RNA

Ribonuclease P (RNase P) is a ribonucleoprotein enzyme that contains a universally conserved, catalytically active RNA component. RNase P RNA requires divalent metal ions for folding, substrate binding, and catalysis. Despite recent advances in understanding the structure of RNase P RNA, no comprehe...

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Bibliografiske detaljer
Main Authors: Kazantsev, Alexei V., Krivenko, Angelika A., Pace, Norman R.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648716/
https://ncbi.nlm.nih.gov/pubmed/19095619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1331809
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