Lataa...
Control of the B Cell-Intrinsic Tolerance Program by c-Cbl and Cbl-b
BCR signaling plays a critical role in B-cell tolerance and activation. Here, we show that mice with B cell-specific ablation of both c-Cbl and Cbl-b (Cbl-dko) manifest systemic lupus erythymatosis (SLE)-like autoimmune disease. The Cbl-dko mutation results in a significant increase in marginal zone...
Tallennettuna:
| Päätekijät: | , , , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2007
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948079/ https://ncbi.nlm.nih.gov/pubmed/17493844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.03.015 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|