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Ablation of Cbl-b provides protection against transplanted and spontaneous tumors

A significant challenge to efforts aimed at inducing effective antitumor immune responses is that CD8(+) T cells, which play a prominent role in these responses, may be unable to respond to tumors that lack costimulatory signals and that are protected by an immune suppressive environment such as tha...

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Autori principali: Chiang, Jeffrey Y., Jang, Ihn Kyung, Hodes, Richard, Gu, Hua
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1810570/
https://ncbi.nlm.nih.gov/pubmed/17364027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29472
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