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Cbl-b deficiency provides protection against UVB-induced skin damage by modulating inflammatory gene signature

Exposure of skin to ultraviolet (UV) radiation induces DNA damage, inflammation, and immune suppression that ultimately lead to skin cancer. However, some of the pathways that regulate these events are poorly understood. We exposed mice to UVB to study its early effects in the absence of Cbl-b, a kn...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Singh, Tej Pratap, Vieyra-Garcia, Pablo A., Wagner, Karin, Penninger, Josef, Wolf, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079082/
https://ncbi.nlm.nih.gov/pubmed/30082827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0858-5
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