Cbl-b Regulates Airway Mucosal Tolerance to Aeroallergen

BACKGROUND: As an E3 ubiquitin ligase and a molecular adaptor, Cbl-b controls the activation threshold of the antigen receptor and negatively regulates CD28 co-stimulation, functioning as an intrinsic mediator of T cell anergy that maintains tolerance. However, the role of Cbl-b in the airway immune...

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Detaylı Bibliyografya
Asıl Yazarlar: Oh, Sun Young, Park, Ju-Un, Zheng, Tao, Kim, Yoon-Keun, Wu, Fan, Cho, Seok Hyun, Barber, Dwayne, Penninger, Josef, Zhu, Zhou
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994994/
https://ncbi.nlm.nih.gov/pubmed/20738317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2010.03593.x
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