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RPA and ATR link transcriptional stress to p53

The mechanisms by which DNA-damaging agents trigger the induction of the stress response protein p53 are poorly understood but may involve alterations of chromatin structure or blockage of either transcription or replication. Here we show that transcription-blocking agents can induce phosphorylation...

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Bibliografische gegevens
Hoofdauteurs: Derheimer, Frederick A., O'Hagan, Heather M., Krueger, Heather M., Hanasoge, Sheela, Paulsen, Michelle T., Ljungman, Mats
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2007
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937543/
https://ncbi.nlm.nih.gov/pubmed/17616578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705317104
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