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Dial 9-1-1 for p53: Mechanisms of p53 Activation by Cellular Stress

The tumor suppressor protein, p53, is part of the cell's emergency team that is called upon following cellular insult. How do cells sense DNA damage and other cellular stresses and what signal transduction pathways are used to alert p53? How is the resulting nuclear accumulation of p53 accompli...

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Detalhes bibliográficos
Autor principal: Ljungman, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: Nature America, Inc. 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1507568/
https://ncbi.nlm.nih.gov/pubmed/10935507
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