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RPA and ATR link transcriptional stress to p53
The mechanisms by which DNA-damaging agents trigger the induction of the stress response protein p53 are poorly understood but may involve alterations of chromatin structure or blockage of either transcription or replication. Here we show that transcription-blocking agents can induce phosphorylation...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1937543/ https://ncbi.nlm.nih.gov/pubmed/17616578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705317104 |
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