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RPA and ATR link transcriptional stress to p53

The mechanisms by which DNA-damaging agents trigger the induction of the stress response protein p53 are poorly understood but may involve alterations of chromatin structure or blockage of either transcription or replication. Here we show that transcription-blocking agents can induce phosphorylation...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Derheimer, Frederick A., O'Hagan, Heather M., Krueger, Heather M., Hanasoge, Sheela, Paulsen, Michelle T., Ljungman, Mats
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1937543/
https://ncbi.nlm.nih.gov/pubmed/17616578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705317104
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