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Hypoxia Links ATR and p53 through Replication Arrest
Previous studies have demonstrated that phosphorylation of human p53 on serine 15 contributes to protein stabilization after DNA damage and that this is mediated by the ATM family of kinases. However, cellular exposure to hypoxia does not induce any detectable level of DNA lesions compared to ionizi...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2002
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC135616/ https://ncbi.nlm.nih.gov/pubmed/11865061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1834-1843.2002 |
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