Hypoxia Links ATR and p53 through Replication Arrest

Previous studies have demonstrated that phosphorylation of human p53 on serine 15 contributes to protein stabilization after DNA damage and that this is mediated by the ATM family of kinases. However, cellular exposure to hypoxia does not induce any detectable level of DNA lesions compared to ionizi...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Hammond, Ester M., Denko, Nicholas C., Dorie, Mary Jo, Abraham, Robert T., Giaccia, Amato J.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 2002
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC135616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11865061/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.6.1834-1843.2002
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