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Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53
In response to ionizing radiation (IR), cells activate a DNA damage response (DDR) pathway to re-program gene expression. Previous studies using total cellular RNA analyses have shown that the stress kinase ATM and the transcription factor p53 are integral components required for induction of IR-ind...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5335570/ https://ncbi.nlm.nih.gov/pubmed/28256581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43598 |
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