Transcriptional and post-transcriptional regulation of the ionizing radiation response by ATM and p53

In response to ionizing radiation (IR), cells activate a DNA damage response (DDR) pathway to re-program gene expression. Previous studies using total cellular RNA analyses have shown that the stress kinase ATM and the transcription factor p53 are integral components required for induction of IR-ind...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Venkata Narayanan, Ishwarya, Paulsen, Michelle T., Bedi, Karan, Berg, Nathan, Ljungman, Emily A., Francia, Sofia, Veloso, Artur, Magnuson, Brian, di Fagagna, Fabrizio d’Adda, Wilson, Thomas E., Ljungman, Mats
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5335570/
https://ncbi.nlm.nih.gov/pubmed/28256581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep43598
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