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Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR
The low-density lipoprotein (LDL) receptor (LDLR) binds to and internalizes lipoproteins that contain apolipoproteinB100 (apoB100) or apolipoproteinE (apoE). Internalization of the apoB100 lipoprotein ligand, LDL, requires the FDNPVY(807) sequence on the LDLR cytoplasmic domain, which binds to the e...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1933400/ https://ncbi.nlm.nih.gov/pubmed/17581630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601769 |
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