Endothelial lipase: direct evidence for a role in HDL metabolism

Por Cohen, Jonathan C.
Publicado em 2003

Emerging LDL Therapies: Using Human Genetics to Discover New Therapeutic Targets for Plasma Lipids

Por Cohen, Jonathan C.
Publicado em 2013

Simple Genetics for a Complex Disease

Por Cohen, Jonathan C., Hobbs, Helen H.
Publicado em 2013

A Weighted False Discovery Rate Control Procedure Reveals Alleles at FOXA2 that Influence Fasting Glucose Levels

Por Xing, Chao, Cohen, Jonathan C., Boerwinkle, Eric
Publicado em 2010

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease

Por Huang, Yongcheng, Cohen, Jonathan C., Hobbs, Helen H.
Publicado em 2011

APOC3, Coronary Disease, and Complexities of Mendelian Randomization

Por Cohen, Jonathan C., Stender, Stefan, Hobbs, Helen H.
Publicado no Cell Metab (2014)

PCSK9: a convertase that coordinates LDL catabolism

Por Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.
Publicado em 2009

Molecular biology of PCSK9: its role in LDL metabolism

Por Horton, Jay D., Cohen, Jonathan C., Hobbs, Helen H.
Publicado em 2007

PNPLA3 and the Pathogenesis and Progression of Pediatric NAFLD

Por Browning, Jeffrey D., Cohen, Jonathan C., Hobbs, Helen H.
Publicado em 2010

Human Fatty Liver Disease: Old Questions and New Insights

Por Cohen, Jonathan C., Horton, Jay D., Hobbs, Helen H.
Publicado em 2011

A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol

Por Guerra, Rudy, Wang, Jinping, Grundy, Scott M., Cohen, Jonathan C.
Publicado em 1997

Dissociation Between APOC3 Variants, Hepatic Triglyceride Content and Insulin Resistance

Por Kozlitina, Julia, Boerwinkle, Eric, Cohen, Jonathan C, Hobbs, Helen H
Publicado em 2011

Genetic Variant in PNPLA3 Associated With Nonalcoholic Fatty Liver Disease in China

Por Li, Yiling, Xing, Chao, Cohen, Jonathan C., Hobbs, Helen H.
Publicado em 2012

Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR

Por Wang, Yan, Huang, Yongcheng, Hobbs, Helen H., Cohen, Jonathan C.
Publicado em 2012

Hepatic Triglyceride Content in Individuals with Reduced Intestinal Cholesterol Absorption Due to Variants in NPC1L1

Por Ramirez, Ruben, Cohen, Jonathan C., Hobbs, Helen H., Browning, Jeffrey D.
Publicado em 2011

The PNPLA3 variant associated with fatty liver disease (I148M) accumulates on lipid droplets by evading ubiquitylation

Por BasuRay, Soumik, Smagris, Eriks, Cohen, Jonathan C., Hobbs, Helen H.
Publicado no Hepatology (2017)

Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes

Por Fahmi, Saleemah, Yang, Chendong, Esmail, Sophie, Hobbs, Helen H., Cohen, Jonathan C.
Publicado em 2008

Identification by whole-genome resequencing of gene defect responsible for severe hypercholesterolemia

Por Rios, Jonathan, Stein, Evan, Shendure, Jay, Hobbs, Helen H., Cohen, Jonathan C.
Publicado em 2010

Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways

Por Mitsche, Matthew A, McDonald, Jeffrey G, Hobbs, Helen H, Cohen, Jonathan C
Publicado no eLife (2015)

Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins

Por Smagris, Eriks, Gilyard, Shenise, BasuRay, Soumik, Cohen, Jonathan C., Hobbs, Helen H.
Publicado no J Biol Chem (2016)