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PCSK9: a convertase that coordinates LDL catabolism
The identification and characterization of proprotein convertase subtilisin-like/kexin type 9 (PCSK9) have provided new insights into LDL metabolism and the causal role of LDL in coronary heart disease (CHD). PCSK9 is a secreted protease that mediates degradation of the LDL receptor by interacting w...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2674748/ https://ncbi.nlm.nih.gov/pubmed/19020338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R800091-JLR200 |
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