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Molecular biology of PCSK9: its role in LDL metabolism
Proprotein convertase subtilisin-like kexin type 9 (PCSK9) is a newly discovered serine protease that destroys low density lipoprotein (LDL) receptors in liver and thereby controls the level of LDL in plasma. Mutations that increase PCSK9 activity cause hypercholesterolemia and coronary heart diseas...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711871/ https://ncbi.nlm.nih.gov/pubmed/17215125 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2006.12.008 |
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