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Functional characterization of genetic variants in NPC1L1 supports the sequencing extremes strategy to identify complex trait genes

Resequencing genes in individuals at extremes of the population distribution constitutes a powerful and efficient strategy to identify sequence variants associated with complex traits. An excess of sequence variants at one extreme relative to the other that is not due to chance or to population stra...

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Detalhes bibliográficos
Main Authors: Fahmi, Saleemah, Yang, Chendong, Esmail, Sophie, Hobbs, Helen H., Cohen, Jonathan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2441721/
https://ncbi.nlm.nih.gov/pubmed/18413323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddn108
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