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Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
An approach to understand quantitative traits was recently proposed based on the finding that nonsynonymous (NS) sequence variants in certain genes are preferentially enriched at one extreme of the population distribution. The NS variants, although individually rare, are cumulatively frequent and in...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413637/ https://ncbi.nlm.nih.gov/pubmed/16449388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508483103 |
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