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Multiple rare variants in NPC1L1 associated with reduced sterol absorption and plasma low-density lipoprotein levels
An approach to understand quantitative traits was recently proposed based on the finding that nonsynonymous (NS) sequence variants in certain genes are preferentially enriched at one extreme of the population distribution. The NS variants, although individually rare, are cumulatively frequent and in...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1413637/ https://ncbi.nlm.nih.gov/pubmed/16449388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508483103 |
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