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Quantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake

The LDL receptor (LDLR) supports efficient uptake of both LDL and VLDL remnants by binding lipoprotein at the cell surface, internalizing lipoprotein through coated pits, and releasing lipoprotein in endocytic compartments before returning to the surface for further rounds of uptake. While many aspe...

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Autori principali: Pompey, Shanica, Zhao, Zhenze, Luby-Phelps, Kate, Michaely, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3617948/
https://ncbi.nlm.nih.gov/pubmed/23296879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033548
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