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Identification of roles for H264, H306, H439, and H635 in acid-dependent lipoprotein release by the LDL receptor

Lipoproteins internalized by the LDL receptor (LDLR) are released from this receptor in endosomes through a process that involves acid-dependent conformational changes in the receptor ectodomain. How acidic pH promotes this release process is not well understood. Here, we assessed roles for six hist...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Lipid Res
मुख्य लेखकों: Dong, Hongyun, Zhao, Zhenze, LeBrun, Drake G., Michaely, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Biochemistry and Molecular Biology 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5282952/
https://ncbi.nlm.nih.gov/pubmed/27895090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M070938
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