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S-nitrosylation of ARH is required for LDL uptake by the LDL receptor

The LDL receptor (LDLR) relies upon endocytic adaptor proteins for internalization of lipoproteins. The results of this study show that the LDLR adaptor autosomal recessive hypercholesterolemia protein (ARH) requires nitric oxide to support LDL uptake. Nitric oxide nitrosylates ARH at C199 and C286,...

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Hlavní autoři: Zhao, Zhenze, Pompey, Shanica, Dong, Hongyun, Weng, Jian, Garuti, Rita, Michaely, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646456/
https://ncbi.nlm.nih.gov/pubmed/23564733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M033167
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