Induction of Tolerance to Human Arylsulfatase A in a Mouse Model of Metachromatic Leukodystrophy

A deficiency of arylsulfatase A (ASA) causes metachromatic leukodystrophy (MLD), a lysosomal storage disorder characterized by accumulation of sulfatide, a severe neurological phenotype and early death. The efficacy of enzyme replacement therapy (ERT) has previously been determined in ASA knockout (...

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Egile Nagusiak: Matzner, Ulrich, Matthes, Frank, Herbst, Eva, Lüllmann-Rauch, Renate, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi, Weigelt, Cecilia, Eistrup, Carl, Fogh, Jens, Gieselmann, Volkmar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: ScholarOne 2007
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933260/
https://ncbi.nlm.nih.gov/pubmed/17660863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00063.Matzner
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