Increasing Sulfatide Synthesis in Myelin-Forming Cells of Arylsulfatase A-Deficient Mice Causes Demyelination and Neurological Symptoms Reminiscent of Human Metachromatic Leukodystrophy

Metachromatic leukodystrophy (MLD) is a lysosomal storage disorder caused by the deficiency of arylsulfatase A (ASA). This results in accumulation of sulfated glycosphingolipids, mainly 3-O-sulfogalactosylceramide (sulfatide), in the nervous system and various other organs. In patients, lipid storag...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ramakrishnan, Hariharasubramanian, Hedayati, Kerstin Khalaj, Lüllmann-Rauch, Renate, Wessig, Carsten, Fewou, Simon Ngamli, Maier, Helena, Goebel, Hans-Hilmar, Gieselmann, Volkmar, Eckhardt, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673125/
https://ncbi.nlm.nih.gov/pubmed/17728461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2287-07.2007
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados