Induction of Tolerance to Human Arylsulfatase A in a Mouse Model of Metachromatic Leukodystrophy

A deficiency of arylsulfatase A (ASA) causes metachromatic leukodystrophy (MLD), a lysosomal storage disorder characterized by accumulation of sulfatide, a severe neurological phenotype and early death. The efficacy of enzyme replacement therapy (ERT) has previously been determined in ASA knockout (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Matzner, Ulrich, Matthes, Frank, Herbst, Eva, Lüllmann-Rauch, Renate, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi, Weigelt, Cecilia, Eistrup, Carl, Fogh, Jens, Gieselmann, Volkmar
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2007
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1933260/
https://ncbi.nlm.nih.gov/pubmed/17660863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/2007-00063.Matzner
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados