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A First-Principles Model of Early Evolution: Emergence of Gene Families, Species, and Preferred Protein Folds
In this work we develop a microscopic physical model of early evolution where phenotype—organism life expectancy—is directly related to genotype—the stability of its proteins in their native conformations—which can be determined exactly in the model. Simulating the model on a computer, we consistent...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1914367/ https://ncbi.nlm.nih.gov/pubmed/17630830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030139 |
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