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Protein stability imposes limits on organism complexity and speed of molecular evolution
Classical population genetics a priori assigns fitness to alleles without considering molecular or functional properties of proteins that these alleles encode. Here we study population dynamics in a model where fitness can be inferred from physical properties of proteins under a physiological assump...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2042177/ https://ncbi.nlm.nih.gov/pubmed/17913881 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705366104 |
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