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Effect of Protein Structure on Evolution of Cotranslational Folding

Cotranslational folding depends on the folding speed and stability of the nascent protein. It remains difficult, however, to predict which proteins cotranslationally fold. Here, we simulate evolution of model proteins to investigate how native structure influences evolution of cotranslational foldin...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Zhao, Victor, Jacobs, William M., Shakhnovich, Eugene I.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499064/
https://ncbi.nlm.nih.gov/pubmed/32857962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.037
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