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Effect of Protein Structure on Evolution of Cotranslational Folding

Cotranslational folding depends on the folding speed and stability of the nascent protein. It remains difficult, however, to predict which proteins cotranslationally fold. Here, we simulate evolution of model proteins to investigate how native structure influences evolution of cotranslational foldin...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Zhao, Victor, Jacobs, William M., Shakhnovich, Eugene I.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499064/
https://ncbi.nlm.nih.gov/pubmed/32857962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.037
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