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Effect of Protein Structure on Evolution of Cotranslational Folding

Cotranslational folding depends on the folding speed and stability of the nascent protein. It remains difficult, however, to predict which proteins cotranslationally fold. Here, we simulate evolution of model proteins to investigate how native structure influences evolution of cotranslational foldin...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Zhao, Victor, Jacobs, William M., Shakhnovich, Eugene I.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499064/
https://ncbi.nlm.nih.gov/pubmed/32857962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.06.037
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