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Evidence of evolutionary selection for cotranslational folding

Recent experiments and simulations have demonstrated that proteins can fold on the ribosome. However, the extent and generality of fitness effects resulting from cotranslational folding remain open questions. Here we report a genome-wide analysis that uncovers evidence of evolutionary selection for...

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Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Jacobs, William M., Shakhnovich, Eugene I.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664504/
https://ncbi.nlm.nih.gov/pubmed/29073068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705772114
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