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Evidence of evolutionary selection for cotranslational folding

Recent experiments and simulations have demonstrated that proteins can fold on the ribosome. However, the extent and generality of fitness effects resulting from cotranslational folding remain open questions. Here we report a genome-wide analysis that uncovers evidence of evolutionary selection for...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Jacobs, William M., Shakhnovich, Eugene I.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664504/
https://ncbi.nlm.nih.gov/pubmed/29073068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705772114
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