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Evidence of evolutionary selection for cotranslational folding

Recent experiments and simulations have demonstrated that proteins can fold on the ribosome. However, the extent and generality of fitness effects resulting from cotranslational folding remain open questions. Here we report a genome-wide analysis that uncovers evidence of evolutionary selection for...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Jacobs, William M., Shakhnovich, Eugene I.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664504/
https://ncbi.nlm.nih.gov/pubmed/29073068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705772114
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