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Evidence of evolutionary selection for cotranslational folding

Recent experiments and simulations have demonstrated that proteins can fold on the ribosome. However, the extent and generality of fitness effects resulting from cotranslational folding remain open questions. Here we report a genome-wide analysis that uncovers evidence of evolutionary selection for...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Jacobs, William M., Shakhnovich, Eugene I.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5664504/
https://ncbi.nlm.nih.gov/pubmed/29073068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705772114
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