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The folding mechanics of a knotted protein

An increasing number of proteins are being discovered with a remarkable and somewhat surprising feature, a knot in their native structures. How the polypeptide chain is able to “knot” itself during the folding process to form these highly intricate protein topologies is not known. Here we perform a...

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Main Authors: Wallin, Stefan, Zeldovich, Konstantin B, Shakhnovich, Eugene I
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692925/
https://ncbi.nlm.nih.gov/pubmed/17368671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.02.035
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