Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.

Perforin-deficient [perforin (-/-)] mice were infected with two strains of JHM virus (JHMV) to analyze the role of perforin-mediated cytotoxicity in acute lethal and subacute central nervous system (CNS) infections. During both acute and subacute infections, the overall mortality of the perforin (-/...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Lin, M T, Stohlman, S A, Hinton, D R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1997
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.383-391.1997
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