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Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.

Perforin-deficient [perforin (-/-)] mice were infected with two strains of JHM virus (JHMV) to analyze the role of perforin-mediated cytotoxicity in acute lethal and subacute central nervous system (CNS) infections. During both acute and subacute infections, the overall mortality of the perforin (-/...

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Detalhes bibliográficos
Main Authors: Lin, M T, Stohlman, S A, Hinton, D R
Formato: Artigo
Idioma:Inglês
Publicado em: 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC191062/
https://ncbi.nlm.nih.gov/pubmed/8985361
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