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Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.

Perforin-deficient [perforin (-/-)] mice were infected with two strains of JHM virus (JHMV) to analyze the role of perforin-mediated cytotoxicity in acute lethal and subacute central nervous system (CNS) infections. During both acute and subacute infections, the overall mortality of the perforin (-/...

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Pubblicato in:J Virol
Autori principali: Lin, M T, Stohlman, S A, Hinton, D R
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1997
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985361/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.383-391.1997
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