Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis.
Perforin-deficient [perforin (-/-)] mice were infected with two strains of JHM virus (JHMV) to analyze the role of perforin-mediated cytotoxicity in acute lethal and subacute central nervous system (CNS) infections. During both acute and subacute infections, the overall mortality of the perforin (-/...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1997
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191062/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8985361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.1.383-391.1997 |
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