Pathogenicity of antigenic variants of murine coronavirus JHM selected with monoclonal antibodies.

To analyze the pathogenesis of the neurotropic murine coronavirus JHMV, we used monoclonal antibodies to the E2 viral glycoprotein to select antigenic variant viruses. Monoclonal antibodies J.7.2 and J.2.2 were shown to bind to topographically distinct regions of the E2 molecule, and the variants se...

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Veröffentlicht in:	J Virol
Hauptverfasser:	Fleming, J O, Trousdale, M D, el-Zaatari, F A, Stohlman, S A, Weiner, L P
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1986
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC252994/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3701929/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.58.3.869-875.1986
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