Gene delivery into malignant glioma by infectivity-enhanced adenovirus: In vivo versus in vitro models

Adenoviral (Ad) vectors demonstrate several attributes of potential utility for glioma gene therapy. Although Ad infection is limited in vitro by low expression levels of the coxsackie-adenoviral receptor (CAR), in vivo studies have shown the efficacy of Ad vectors as gene delivery vectors. To evalu...

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Detalhes bibliográficos
Main Authors: Van Houdt, Winan J., Wu, Hongju, Glasgow, Joel N., Lamfers, Martine L., Dirven, Clemens M., Gillespie, G. Yancey, Curiel, David T., Haviv, Yosef S.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2007
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1907413/
https://ncbi.nlm.nih.gov/pubmed/17522331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2007-017
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