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In vivo gene delivery by embryonic-stem-cell–derived astrocytes for malignant gliomas

The treatment of malignant gliomas with current therapies remains a challenge in neurooncology. Our recent work showed that embryonic stem cell (ESC)-derived astrocytes conditionally expressing genes can be used to induce apoptosis in malignant glioma cells in vitro. The tumor necrosis factor–relate...

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Autors principals: Uzzaman, Mahmud, Keller, Gordon, Germano, Isabelle M.
Format: Artigo
Idioma:Inglês
Publicat: Duke University Press 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718981/
https://ncbi.nlm.nih.gov/pubmed/18676359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2008-056
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