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Embryonic stem cell (ESC)-mediated transgene delivery induces growth suppression, apoptosis, radiosensitization, and overcomes temozolomide resistance in malignant gliomas

High-grade gliomas are among the most lethal of all cancers. Despite considerable advances in multi-modality treatment, including surgery, radiotherapy, and chemotherapy, the overall prognosis for patients with this disease remains dismal. Currently available treatments necessitate the development o...

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Detalhes bibliográficos
Main Authors: Germano, Isabelle M., Emdad, Luni, Qadeer, Zulekha A., Uzzaman, Mahmud
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923667/
https://ncbi.nlm.nih.gov/pubmed/20523363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2010.31
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