Enhanced Gene Delivery to Human Primary Endothelial Cells Using Tropism-Modified Adenovirus Vectors

Endothelial cells have been noted to have relatively low expression of the native receptor for adenovirus serotype 5 (Ad5), coxsackie and adenovirus receptor (CAR), and are thus refractory to Ad5 infection. In this study, we hypothesize that increases in the infectivity of Ad5 in primary human pulmo...

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Hlavní autoři: Preuss, Meredith A., Glasgow, Joel N., Everts, Maaike, Stoff-Khalili, Mariam A., Wu, Hongju, Curiel, David T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761693/
https://ncbi.nlm.nih.gov/pubmed/19834585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875037000801010007
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