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Local interstitial delivery of z-butylidenephthalide by polymer wafers against malignant human gliomas

We have shown that the natural compound z-butylidenephthalide (Bdph), isolated from the chloroform extract of Angelica sinensis, has antitumor effects. Because of the limitation of the blood-brain barrier, the Bdph dosage required for treatment of glioma is relatively high. To solve this problem, we...

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Autors principals: Harn, Horng-Jyh, Lin, Shinn-Zong, Lin, Po-Cheng, Liu, Cyong-Yue, Liu, Po-Yen, Chang, Li-Fu, Yen, Ssu-Yin, Hsieh, Dean-Kuo, Liu, Fu-Chen, Tai, Dar-Fu, Chiou, Tzyy-Wen
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3107093/
https://ncbi.nlm.nih.gov/pubmed/21565841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor021
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