Non-Canonical Regulation of Type I Collagen through Promoter Binding of SOX2 and Its Contribution to Ameliorating Pulmonary Fibrosis by Butylidenephthalide

Pulmonary fibrosis is a fatal respiratory disease that gradually leads to dyspnea, mainly accompanied by excessive collagen production in the fibroblast and myofibroblast through mechanisms such as abnormal alveolar epithelial cells remodeling and stimulation of the extracellular matrix (ECM). Our r...

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Udgivet i:Int J Mol Sci
Main Authors: Chuang, Hong-Meng, Ho, Li-Ing, Huang, Mao-Hsuan, Huang, Kun-Lun, Chiou, Tzyy-Wen, Lin, Shinn-Zong, Su, Hong-Lin, Harn, Horng-Jyh
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213013/
https://ncbi.nlm.nih.gov/pubmed/30287739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19103024
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