Primary Human Immunodeficiency Virus Type 1 Nef Alleles Show Major Differences in Pathogenicity in Transgenic Mice

Eitemau Tebyg

• Expression of Simian Immunodeficiency Virus nef in Immune Cells of Transgenic Mice Leads to a Severe AIDS-Like Disease
  gan: Simard, Marie-Chantal, et al.
  Cyhoeddwyd: (2002)
• Selective Expression of Human Immunodeficiency Virus Nef in Specific Immune Cell Populations of Transgenic Mice Is Associated with Distinct AIDS-Like Phenotypes
  gan: Hanna, Zaher, et al.
  Cyhoeddwyd: (2009)
• Adult AIDS-Like Disease in a Novel Inducible Human Immunodeficiency Virus Type 1 Nef Transgenic Mouse Model: CD4(+) T-Cell Activation Is Nef Dependent and Can Occur in the Absence of Lymphophenia
  gan: Rahim, Mir Munir Ahmed, et al.
  Cyhoeddwyd: (2009)
• CD4(+) T Cells from CD4C/HIV(Nef) Transgenic Mice Show Enhanced Activation In Vivo with Impaired Proliferation In Vitro but Are Dispensable for the Development of a Severe AIDS-Like Organ Disease
  gan: Weng, Xiaoduan, et al.
  Cyhoeddwyd: (2004)
• The Nef-Mediated AIDS-Like Disease of CD4C/Human Immunodeficiency Virus Transgenic Mice Is Associated with Increased Fas/FasL Expression on T Cells and T-Cell Death but Is Not Prevented in Fas-, FasL-, Tumor Necrosis Factor Receptor 1-, or Interleukin-1β-Converting Enzyme-Deficient or Bcl2-Expressing Transgenic Mice
  gan: Priceputu, Elena, et al.
  Cyhoeddwyd: (2005)