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Primary Human Immunodeficiency Virus Type 1 Nef Alleles Show Major Differences in Pathogenicity in Transgenic Mice

We previously reported that the human immunodeficiency virus type 1 NL4-3 Nef is necessary and sufficient to induce a severe AIDS-like disease in transgenic (Tg) mice when the protein is expressed under the regulatory sequences of the human CD4 gene. We have now assayed additional Nef alleles (SF2,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Priceputu, Elena, Hanna, Zaher, Hu, Chunyan, Simard, Marie-Chantal, Vincent, Patrick, Wildum, Steffen, Schindler, Michael, Kirchhoff, Frank, Jolicoeur, Paul
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2007
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1900134/
https://ncbi.nlm.nih.gov/pubmed/17314161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02691-06
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